Detail Hasil Pencarian
Pengaruh Fisioterapi Terhadap Perbaikan Rasa Nyeri Pada Penderita Osteoartritis Lutut Yang Mendapat Terapi Parasetamol
|Pengarang||:||Nyoman Kertia, Siti Nurdjanah|
|Jurnal||:||Berkala Ilmu Kedokteran 2006, XXXVIII(2)|
|Summary / Kata Kunci||:||Nyoman Kertia, Siti Nurdjanah - Impact of physiotherapy on pain improvement in patients with knee osteoarthritis who took paracetamol
Background: Osteoarthritis (OA) of the knee is a disease caused by several etiologies but similar biology, morphology and clinical presentation. It doesn't only affect joint cartilage, but also subchondral bone, ligament, capsule, membrane of joint and periarticular muscles. Chief complaints in OA of the knee are pain and physical disability. In OA of the knee there is lower limb weakness, particularly quadriceps muscles and the weakness severity is related to pain and disability.
Objective: To know the combination of physiotherapy and paracetamol compound to paracetamol alone in OA of the knee.
Methods: This study is a randomized controlled trial in OA of the knee in patients with moderate pain in Internal Medicine Department Outpatients Clinic, Dr. Sardjito Hospital, Yogyakarta. Patients were randomly divided into 2 groups. Treatment group (17 patients) took physiotherapy and paracetamol. Control group (19 patients) took paracetamol only. Physiotherapy was performed in Medical Rehabilitation Clinic with isometric exercise three times weekly and paracetamol 500 mg three times daily for 4 weeks. Pain intensity was measured by visual analogue scale (VAS) 100 mm before and after treatment.
Result: There was significant decrease in the mean of pain intensity before and after treatment between treatment and control groups as much as 6.65 ± 5.134 mm (95% CI 32.14 to 41.15; p < 0.0001) and 28.84 ± 8.760 mm (95% CI 26.37 to 31.32; p < 0.0001), respectively. The decrease of pain intensity was significantly different between two goups (95% CI 3.004 to 12.606; p=0.002) after 4 weeks of treatment. No serious adverse events were attributable resulted from paracetamol treatment.
Conclusion: Pain intensity in OA of the knee patients who took paracetamol 500 mg three times daily and physiotherapy improved significantly than paracetamol only for 4 weeks of treatment.
Key words: knee osteoarthritis, pain, VAS, physiotherapy, paracetamol.
|(tidak ada sitasi)|
|1.||Altman RD, Hochberg MC, Moskowitz RW, Schnitzer C.J., Recommendations for the Medical Management of Osteoarthritis of the Hip and Knee., 2000|
|2.||Americans Geriatrics Society Panel on Exercise and Osteoarthritis (AGS)., Exercise Prescription for older Adults with Osteoarthritis Pain: Consensus Practice Recommendations., 2001|
|3.||Bennel K, Hinman R, Exercise as a Treatment for Osteoarthritis., 2005|
|4.||Berlin P, Keddad K, Jolivet-Landreau I, Acetaminophen as Symptomatic Treatment of Pain from Osteoarthritis., 2004|
|5.||Burns M J, Friedman S I.., Larson, A.M., Pathophysiology and Diagnosis of Acetaminophen (Parasetamol) Intoxication., 2005|
|6.||Dougados M, LeClaire P, Van der Heijde D, Bloch DA, Bellamy N, Altman RD, A Report of the Osteoarthritis Research Society International Standing Committee for Clinical Trials Response Criteria Initiative., 2000|
|7.||Dougados M, Ravaud P., Exercise Therapy in Patients with Osteoartritis of the Hip or Knee, 2001|
|8.||DT. Felson , RC. Lawrence , PA.Dieppe, Osteoarthritis: New Insights. Part 1. The Disease and Its Risk Factors., 2000|
|9.||Fransen M, Mcconnel S, Bell M, Exercise for Osteoarthritis of the Hip or Knee, 2003|
|10.||GD. Benson, RS. Koff , KG. Tolman, The Therapeutic Use of Acetaminophen in Patients with Liver Disease., 2005|
|11.||GD. Deyle, NE Henderson , RL. Matekel , MG, Ryder, MB. Garber , SC.Allison, Effectiveness of Manual Physical Therapy and Exercise in Osteoarthritis of th Knee., 2000|
|12.||Geba GP, Weaver A L, Pas AB, Dixon ME, Schnitzer TJ., . Efficacy of Rofecoxib, Celecoxib, and Acetaminophen in Osteoarthritis of the Knee, 2002|
|13.||Graham GG, Scott KF, Day RO., Tolerability of Paracetamol., 2005|
|14.||Graham GG, Scott KF., Mechanism of Action of Paracetamol., 2005|
|15.||Huang MH, Lin YS, Yang RC, Lee CL, . A Comparison of Various Therapeutic Exercises on the Functional Statusof Patients with Knee Osieoarthritis, 2003|
|16.||I. Boutron, F. Tubach, B. Giraudeau, P. Ravaud, Methodological Difference in Clinical Trial Non-pharmacological and Pharmacological Treatments of Hip and Knee Osteoarthritis, 2003|
|17.||Isbagio H., Osteoartrtitis: Klinis dan Terapi., 2003|
|18.||Jordan KM, Arden N, Doherty M, Bannwarth Dieppe 'P, G.nther KP, Hauselmann Hi. et al, EULAR Recommendations 2003 : an Evidence Based approach to the Management of Knee Osteoarthritis: Report of a task force of the Standing, 2003|
|19.||Kasjmir YI, Isbagio H, Pemeriksaan Klinis dan Pengukuran Nyeri., 2004|
|20.||Lequesne MG, Samson M., Indices of Severity in Osteoarthritis for Weight Bearing Joints, 1991|
|21.||Manek NJ., Medical Management of Osteoarthritis., 2001|
|22.||Pavelka K., Symptomatic Treatment of Osteoarthritis: Paracetamol or NSAIDs, 2004|
|23.||Purnomo LB, Kertia N, Savitri K, Asdie AH, Raharjo P., Nilai Kesepakatan Dokter-pasien dan Pasien-pasien dan Indek Lequesne, 1999|
|24.||Roddy E, Zhang W, Doherty M, Arden NIC, Barlow J, Birrel, F. et al., Evidence-based Recommendations for the Role of Exercise in the Management ofOsteoarthritis of Hip or Knee - the MOVE Consens, 2005|
|25.||Shamoon, M., Hochberg, M.C, Treatment of Osteoarthritis with Acetaminophen: Efficacy, Safety, and Comparison with NonSteroidal Antiirdlammatory Drugs., 2000|
|26.||Shiozaki H, Koga Y, Omori G, Tamaki M., Obesity and Osteoarthritis of the Knee in Women: Results from the Matsudai Knee Osteoarthritis Survey, 1999|
|27.||Soklca T., Assessment of Pain in Patients with Rheumatic Disease Best Pract Res Clin Peat G, McCamey R, Croft P. 2001. Knee Pain and Osteoarthritis in Older Adults, 2003|
|28.||Topp R, Woolley S, Hornyak J, Khuder S, Kahaleh B., The Effect of Dynamic versus Isometric Resistance Training on Pain and Functioning among Adults withOsteoarthritis of the Knee, 2002|
|29.||van Baar ME, Assendelft WJJ, Dekker 1, Oostendorp RAB, Bijlsma JWJ., Effectiveness of Exercise Therapy in Patients with Osteoarthritis of the Hip or Knee. A Systematic Review of Randomized Clinical Trials, 1999|
|30.||Woolf CJ., Pain: Moving from Symptom Control toward Mechanism-Spe_sitic Pharmacologic Management., 2004|
|31.||Zhang W, Jones A, Doherty M, Does Parasetamol (Acetaminophen) reduce the Pain of Osteoarthritis ?: A Meta-analysis of Randomized Controlled Trials., 2004|
|32.||Zoppi M, Beneforti E., Joint Pain. Curr Rev Pain,, 1999|